Pign | phosphatidylinositol glycan anchor biosynthesis, class N

Physiological systems

21 / 24 physiological systems tested

14 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Integument Growth/size/body region Craniofacial Cardiovascular system Renal/urinary system Homeostasis/metabolism Embryo Nervous system Vision/eye Liver/biliary system Behavior/neurological Mortality/aging

7 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Pign^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal blood vessel morphology	1 supporting dataset	Pign^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal skin morphology	1 supporting dataset	Pign^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Pign^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Pign^em1(IMPC)Mbp	heterozygote	Early adult	7.42x10^-10
small kidney	1 supporting dataset	Pign^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
small liver	1 supporting dataset	Pign^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
edema	1 supporting dataset	Pign^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
facial cleft	1 supporting dataset	Pign^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
anophthalmia	1 supporting dataset	Pign^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Pign.

Associated images

Loading...

Histopathology

There is no histopathology data found for Pign.

IMPC related publications

Loading...

External links

No external links available for Pign.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Pign^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Pign^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes