Exoc6 | exocyst complex component 6
Physiological systems
21 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Integument Behavior/neurological Mortality/aging
18 No significant impact
3 Not tested
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Exoc6tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| pallor | 1 supporting dataset | Exoc6tm1b(EUCOMM)Wtsi | homozygote | E18.5 | N/A * | ||
| unresponsive to tactile stimuli | 1 supporting dataset | Exoc6tm1b(EUCOMM)Wtsi | homozygote | E18.5 | N/A * | ||
| abnormal skin appearance | 1 supporting dataset | Exoc6tm1b(EUCOMM)Wtsi | homozygote | E18.5 | N/A * | ||
| unresponsive to tactile stimuli | 1 supporting dataset | Exoc6tm1b(EUCOMM)Wtsi | heterozygote | E18.5 | N/A * | ||
| hyperactivity | 1 supporting dataset | Exoc6tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 7.71x10-5 |
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External links
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| Exoc6tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Exoc6tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Exoc6tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |