Npas3 | neuronal PAS domain protein 3
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Behavior/neurological Mortality/aging
17 No significant impact
5 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
128Embryo tissues
| unresponsive to tactile stimuli | 1 supporting dataset | Npas3tm1b(KOMP)Wtsi | heterozygote | E18.5 | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Npas3tm1b(KOMP)Wtsi | heterozygote | E18.5 | N/A * | ||
| unresponsive to tactile stimuli | 1 supporting dataset | Npas3tm1b(KOMP)Wtsi | homozygote | E18.5 | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Npas3tm1b(KOMP)Wtsi | homozygote | E18.5 | N/A * | ||
| increased startle reflex | 1 supporting dataset | Npas3tm1b(KOMP)Wtsi | heterozygote | Early adult | 7.2x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Npas3tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Npas3.
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| Npas3tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Npas3tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Npas3tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |