Nup62 | nucleoporin 62

GeneMGI:1351500Synonyms: D7Ertd649e, p62, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Adipose tissue Vision/eye Skeleton Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:51Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal retina inner nuclear layer morphology	2 supporting datasets	Nup62^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.14x10^-8
preweaning lethality, complete penetrance	3 supporting datasets	Nup62^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased total retina thickness	2 supporting datasets	Nup62^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	8.65x10^-11
increased bone mineral content	2 supporting datasets	Nup62^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.57x10^-6
decreased total body fat amount	1 supporting dataset	Nup62^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	7.96x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nup62.

Associated images

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Histopathology

There is no histopathology data found for Nup62.

IMPC related publications

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External links

No external links available for Nup62.

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*Nup62^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Nup62^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Nup62^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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