Cartpt | CART prepropeptide

GeneMGI:1351330Synonyms: Cart

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Digestive/alimentary Vision/eye Behavior/neurological Renal/urinary system

17 No significant impact

3 Not tested

Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology1 supporting datasetCartptem1(IMPC)MbphomozygoteEarly adultN/A * 
enhanced contextual conditioning behavior1 supporting datasetCartptem1(IMPC)MbphomozygoteEarly adult1.09x10-5 
small kidney1 supporting datasetCartptem1(IMPC)MbphomozygoteEarly adultN/A * 
increased startle reflex1 supporting datasetCartptem1(IMPC)MbphomozygoteEarly adult5.7x10-5 
abnormal cecum morphology1 supporting datasetCartptem1(IMPC)MbphomozygoteEarly adultN/A * 
cataract1 supporting datasetCartptem1(IMPC)MbphomozygoteEarly adult1.06x10-7 
abnormal vitreous body morphology1 supporting datasetCartptem1(IMPC)MbphomozygoteEarly adult1.05x10-7 
decreased exploration in new environment1 supporting datasetCartptem1(IMPC)MbphomozygoteEarly adult3.38x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cartptem1(IMPC)MbpWhole-gene deletionmouse
Cartpttm96437(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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