Tcirg1 | T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3

GeneMGI:1350931Synonyms: TIRC7, Atp6i, +3 more

Physiological systems

24 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

17 No significant impact

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

5Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased hematocrit	1 supporting dataset	Tcirg1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	4.34x10^-5
enlarged heart	1 supporting dataset	Tcirg1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
increased circulating iron level	1 supporting dataset	Tcirg1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	8.57x10^-5
no spontaneous movement	1 supporting dataset	Tcirg1^{em1(IMPC)Ccpcz}	homozygote	E18.5	N/A ^*
increased kidney weight	1 supporting dataset	Tcirg1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	4.08x10^-5
abnormal retina vasculature morphology	1 supporting dataset	Tcirg1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.17x10^-6
abnormal heart morphology	1 supporting dataset	Tcirg1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tcirg1.

Associated images

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Histopathology

There is no histopathology data found for Tcirg1.

IMPC related publications

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External links

No external links available for Tcirg1.

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*Tcirg1^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Tcirg1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Tcirg1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Tcirg1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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