Asns | asparagine synthetase

GeneMGI:1350929

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina pigmentation	2 supporting datasets	Asns^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.77x10^-6
increased heart weight	1 supporting dataset	Asns^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.53x10^-5
abnormal glucose homeostasis	1 supporting dataset	Asns^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.03x10^-5
decreased hemoglobin content	1 supporting dataset	Asns^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.59x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Asns.

Associated images

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Histopathology

There is no histopathology data found for Asns.

IMPC related publications

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External links

No external links available for Asns.

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*Asns^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Asns^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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