Irf5 | interferon regulatory factor 5

GeneMGI:1350924Synonyms: mirf5

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Hematopoietic system Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

6Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



decreased leukocyte cell number	1 supporting dataset	Irf5^{tm1e(EUCOMM)Wtsi}	homozygote	Early adult	2.83x10^-5
decreased CD4-positive, alpha-beta memory T cell number	2 supporting datasets	Irf5^{tm1e(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Irf5^em1(IMPC)Bay	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Irf5.

Associated images

Loading...

Histopathology

There is no histopathology data found for Irf5.

IMPC related publications

Loading...

External links

No external links available for Irf5.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Irf5^em1(IMPC)Bay*	Point Mutation	‌	mouse
*Irf5^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Irf5^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell mouse

My Genes