Nherf1 | NHERF family PDZ scaffold protein 1

GeneMGI:1349482Synonyms: Slc9a3r1, NHERF1, +3 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased leukocyte cell number	1 supporting dataset	Nherf1^em1(IMPC)H	homozygote	Early adult	1.32x10^-7
increased basophil cell number	1 supporting dataset	Nherf1^em1(IMPC)H	homozygote	Early adult	3.78x10^-6
decreased circulating iron level	1 supporting dataset	Nherf1^em1(IMPC)H	homozygote	Early adult	8.57x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nherf1.

Associated images

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Histopathology

There is no histopathology data found for Nherf1.

IMPC related publications

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External links

No external links available for Nherf1.

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*Nherf1^em1(IMPC)H*	Indel	‌	mouse
*Nherf1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Nherf1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Nherf1^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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