Ppp2r5e | protein phosphatase 2, regulatory subunit B', epsilon

GeneMGI:1349473Synonyms: B56beta, 4633401M22Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Hearing/vestibular/ear Hematopoietic system Behavior/neurological Skeleton

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased exploration in new environment	1 supporting dataset	Ppp2r5e^{em1(IMPC)Marc}	homozygote	Early adult	1.01x10^-8
decreased bone mineral content	2 supporting datasets	Ppp2r5e^{em1(IMPC)Marc}	homozygote	Early adult	4.01x10^-5
increased mean corpuscular volume	1 supporting dataset	Ppp2r5e^{em1(IMPC)Marc}	homozygote	Early adult	1.08x10^-17
abnormal locomotor behavior	1 supporting dataset	Ppp2r5e^{em1(IMPC)Marc}	homozygote	Early adult	1.69x10^-5
abnormal auditory brainstem response	2 supporting datasets	Ppp2r5e^{em1(IMPC)Marc}	homozygote	Early adult	4.98x10^-5
decreased locomotor activity	5 supporting datasets	Ppp2r5e^{em1(IMPC)Marc}	homozygote	Early adult	2.2x10^-6
abnormal bone structure	1 supporting dataset	Ppp2r5e^{em1(IMPC)Marc}	homozygote	Early adult	3.53x10^-5
decreased mean platelet volume	1 supporting dataset	Ppp2r5e^{em1(IMPC)Marc}	homozygote	Early adult	5.58x10^-7
increased hematocrit	1 supporting dataset	Ppp2r5e^{em1(IMPC)Marc}	homozygote	Early adult	5.39x10^-6
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Ppp2r5e^{em1(IMPC)Marc}	homozygote	Early adult	2.6x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ppp2r5e.

Associated images

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Histopathology

There is no histopathology data found for Ppp2r5e.

IMPC related publications

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External links

No external links available for Ppp2r5e.

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*Ppp2r5e^{em1(IMPC)Marc}*	Deletion	‌	mouse
*Ppp2r5e^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ppp2r5e^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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