Serinc3 | serine incorporator 3

GeneMGI:1349457Synonyms: DIFF33, TMS-1, +2 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hearing/vestibular/ear Skeleton

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal auditory brainstem response	1 supporting dataset	Serinc3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.49x10^-5
decreased circulating magnesium level	1 supporting dataset	Serinc3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.58x10^-6
decreased bone mineral content	1 supporting dataset	Serinc3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.37x10^-6
decreased bone mineral density	1 supporting dataset	Serinc3^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.65x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Serinc3.

Associated images

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Histopathology

There is no histopathology data found for Serinc3.

IMPC related publications

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External links

No external links available for Serinc3.

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*Serinc3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Serinc3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Serinc3^{tm35556(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Serinc3^{tm355714(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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