Cenph | centromere protein H

GeneMGI:1349448Synonyms: 2810046K12Rik, 2610042E16Rik, +4 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating HDL cholesterol level1 supporting datasetCenphtm1b(EUCOMM)HmguheterozygoteEarly adult1.46x10-5 
preweaning lethality, complete penetrance1 supporting datasetCenphtm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cenphtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Cenphtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Cenphtm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Cenphtm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Cenphtm3a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Cenphtm3e(EUCOMM)HmguTargeted, non-conditional allelees cell

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