Cln8 | CLN8 transmembrane ER and ERGIC protein
Physiological systems
20 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Cardiovascular system Renal/urinary system
12 No significant impact
4 Not tested
Data collections
Gene metrics:14Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased circulating phosphate level | 1 supporting dataset | Cln8em1(IMPC)Mbp | homozygote | Early adult | 4.87x10-5 | ||
enlarged spleen | 2 supporting datasets | Cln8em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
abnormal retina morphology | 1 supporting dataset | Cln8em1(IMPC)Mbp | homozygote | Early adult | 5.3x10-5 | ||
abnormal vitreous body morphology | 1 supporting dataset | Cln8em1(IMPC)Mbp | homozygote | Early adult | 5.99x10-5 | ||
small liver | 1 supporting dataset | Cln8em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
abnormal kidney morphology | 1 supporting dataset | Cln8em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
cataract | 1 supporting dataset | Cln8em1(IMPC)Mbp | homozygote | Early adult | 6.35x10-5 | ||
increased circulating serum albumin level | 1 supporting dataset | Cln8em1(IMPC)Mbp | homozygote | Early adult | 1.47x10-5 | ||
enlarged kidney | 1 supporting dataset | Cln8em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
increased heart weight | 2 supporting datasets | Cln8em1(IMPC)Mbp | homozygote | Early adult | 2.17x10-5 |
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External links
No external links available for Cln8.
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Cln8em1(IMPC)Mbp | Intra-exon deletion | | mouse |
Cln8tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
Cln8tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Cln8tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |