Abcd4 | ATP-binding cassette, sub-family D member 4
Physiological systems
19 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Behavior/neurological
18 No significant impact
5 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal response to tactile stimuli | 1 supporting dataset | Abcd4tm1a(EUCOMM)Hmgu | homozygote | Early adult | 3.05x10-7 | ||
| abnormal response to new environment | 1 supporting dataset | Abcd4tm1a(EUCOMM)Hmgu | homozygote | Early adult | 9.2x10-7 |
| | | | | | | | | | |
Human diseases caused by Abcd4 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Abcd4.
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| Abcd4tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Abcd4tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Abcd4tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Abcd4tm83313(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |