Abcd3 | ATP-binding cassette, sub-family D member 3

GeneMGI:1349216Synonyms: Pxmp1, PMP70

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Adipose tissue Growth/size/body region Behavior/neurological Skeleton

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased circulating total protein level	1 supporting dataset	Abcd3^em1(IMPC)J	homozygote	Early adult	4.7x10^-7
abnormal coat/ hair morphology	1 supporting dataset	Abcd3^em1(IMPC)J	homozygote	Late adult	7.76x10^-6
abnormal coat/hair pigmentation	1 supporting dataset	Abcd3^em1(IMPC)J	homozygote	Late adult	3.11x10^-5
increased fasting circulating glucose level	1 supporting dataset	Abcd3^em1(IMPC)J	homozygote	Late adult	2.34x10^-6
impaired righting response	1 supporting dataset	Abcd3^em1(IMPC)J	homozygote	Late adult	1.02x10^-6
increased fasting circulating glucose level	1 supporting dataset	Abcd3^em1(IMPC)J	homozygote	Early adult	8.56x10^-7
increased lean body mass	1 supporting dataset	Abcd3^em1(IMPC)J	homozygote	Late adult	7.68x10^-10
decreased total body fat amount	1 supporting dataset	Abcd3^em1(IMPC)J	homozygote	Late adult	3.76x10^-8
decreased circulating triglyceride level	1 supporting dataset	Abcd3^em1(IMPC)J	homozygote	Early adult	1x10^-9
decreased bone mineral density	1 supporting dataset	Abcd3^em1(IMPC)J	homozygote	Early adult	1.86x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Abcd3.

Associated images

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Histopathology

There is no histopathology data found for Abcd3.

IMPC related publications

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External links

No external links available for Abcd3.

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*Abcd3^em1(IMPC)J*	Exon Deletion	‌	mouse
*Abcd3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Abcd3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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