Sdc4 | syndecan 4
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Vision/eye Hematopoietic system Cardiovascular system
14 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| increased neutrophil cell number | 2 supporting datasets | Sdc4tm2b(KOMP)Wtsi | homozygote | Early adult | 2.01x10-11 | ||
| decreased circulating total protein level | 1 supporting dataset | Sdc4tm2b(KOMP)Wtsi | homozygote | Early adult | 7.91x10-5 | ||
| abnormal retina blood vessel morphology | 1 supporting dataset | Sdc4tm2b(KOMP)Wtsi | heterozygote | Early adult | 5.09x10-5 | ||
| decreased mean platelet volume | 1 supporting dataset | Sdc4tm2b(KOMP)Wtsi | homozygote | Early adult | 2.63x10-5 | ||
| decreased lymphocyte cell number | 1 supporting dataset | Sdc4tm2b(KOMP)Wtsi | homozygote | Early adult | 6.96x10-9 | ||
| increased red blood cell distribution width | 1 supporting dataset | Sdc4tm2b(KOMP)Wtsi | homozygote | Early adult | 1.31x10-7 | ||
| mydriasis | 1 supporting dataset | Sdc4tm2b(KOMP)Wtsi | heterozygote | Early adult | 7.33x10-8 | ||
| decreased circulating serum albumin level | 1 supporting dataset | Sdc4tm2b(KOMP)Wtsi | homozygote | Early adult | 8.12x10-5 |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 100% (2/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 100% (2/2) | 0.19% (1/533) |
| bone | heterozygote | n/a | 100% (2/2) | 0% (0/394) |
| brain | heterozygote | n/a | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 100% (2/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 100% (2/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 100% (2/2) | 0.22% (1/454) |
| cerebellum | heterozygote | n/a | 100% (2/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 100% (2/2) | 0.41% (2/491) |
| esophagus | heterozygote | n/a | 100% (2/2) | 1.67% (7/419) |
External links
No external links available for Sdc4.
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| Sdc4tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Sdc4tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Sdc4tm2b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Sdc4tm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |