Sdc3 | syndecan 3
Physiological systems
14 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Integument Skeleton
12 No significant impact
10 Not tested
Data collections
Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal hair growth | 1 supporting dataset | Sdc3em1(IMPC)Wtsi | homozygote | Early adult | 4.8x10-5 | ||
| decreased bone mineral content | 1 supporting dataset | Sdc3em1(IMPC)Wtsi | homozygote | Early adult | 3.24x10-5 |
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Human diseases caused by Sdc3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Sdc3.
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| Sdc3em1(IMPC)Wtsi | Point Mutation | | mouse |
| Sdc3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Sdc3tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Sdc3tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |