Sdc1 | syndecan 1

GeneMGI:1349162Synonyms: syn-1, Synd, +2 more

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating creatinine level1 supporting datasetSdc1em1(IMPC)HhomozygoteEarly adult9.89x10-13 
increased circulating HDL cholesterol level1 supporting datasetSdc1em1(IMPC)HhomozygoteEarly adult2.4x10-6 
improved glucose tolerance1 supporting datasetSdc1em1(IMPC)HhomozygoteEarly adult4.94x10-5 
increased circulating cholesterol level1 supporting datasetSdc1em1(IMPC)HhomozygoteEarly adult3.3x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sdc1em1(IMPC)HExon Deletionmouse
Sdc1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Sdc1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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