Ror2 | receptor tyrosine kinase-like orphan receptor 2

GeneMGI:1347521Synonyms: Ntrkr2

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Embryo Growth/size/body region Digestive/alimentary Limbs/digits/tail Vision/eye Behavior/neurological Cardiovascular system Mortality/aging Craniofacial

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal vitreous body morphology	1 supporting dataset	Ror2^em1(IMPC)Mbp	heterozygote	Early adult	5.99x10^-5
abnormal limb morphology	1 supporting dataset	Ror2^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Ror2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cleft palate	1 supporting dataset	Ror2^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal placenta vasculature	1 supporting dataset	Ror2^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal tail morphology	1 supporting dataset	Ror2^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
persistence of hyaloid vascular system	1 supporting dataset	Ror2^em1(IMPC)Mbp	heterozygote	Early adult	5.34x10^-7
embryonic growth retardation	1 supporting dataset	Ror2^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal craniofacial morphology	1 supporting dataset	Ror2^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal placenta morphology	1 supporting dataset	Ror2^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ror2.

Associated images

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Histopathology

There is no histopathology data found for Ror2.

IMPC related publications

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External links

No external links available for Ror2.

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*Ror2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Ror2^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Ror2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ror2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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