Ror1 | receptor tyrosine kinase-like orphan receptor 1

GeneMGI:1347520Synonyms: Ntrkr1, 2810404D04Rik

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Nervous system Hematopoietic system Mortality/aging Renal/urinary system

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



enlarged spleen	1 supporting dataset	Ror1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Ror1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
increased prepulse inhibition	1 supporting dataset	Ror1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	3.47x10^-5
enlarged thymus	1 supporting dataset	Ror1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Ror1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Ror1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
hydrometra	1 supporting dataset	Ror1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
small kidney	1 supporting dataset	Ror1^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Ror1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ror1.

Associated images

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Histopathology

There is no histopathology data found for Ror1.

IMPC related publications

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External links

No external links available for Ror1.

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*Ror1^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Ror1^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Ror1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ror1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Ror1^{tm441(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Ror1^{tm441(L1L2_st1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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