Hunk | hormonally upregulated Neu-associated kinase

GeneMGI:1347352Synonyms: Bstk1, Mak-v

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Nervous system Cardiovascular system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal digit morphology	1 supporting dataset	Hunk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.51x10^-8
increased circulating glucose level	1 supporting dataset	Hunk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.67x10^-5
decreased prepulse inhibition	3 supporting datasets	Hunk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.84x10^-6
increased heart rate	1 supporting dataset	Hunk^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.35x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hunk.

Associated images

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Histopathology

There is no histopathology data found for Hunk.

IMPC related publications

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External links

No external links available for Hunk.

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*Hunk^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Hunk^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Hunk^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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