Parg | poly (ADP-ribose) glycohydrolase
GeneMGI:1347094
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Immune system Hematopoietic system Mortality/aging
17 No significant impact
4 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
31Embryo tissues
| embryonic lethality prior to organogenesis | 1 supporting dataset | Pargtm2b(KOMP)Mbp | homozygote | E9.5 | N/A * | ||
| decreased leukocyte cell number | 1 supporting dataset | Pargtm2b(KOMP)Mbp | heterozygote | Early adult | 1.82x10-8 | ||
| preweaning lethality, complete penetrance | 2 supporting datasets | Pargtm2b(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Pargtm2b(KOMP)Mbp | homozygote | E12.5 | N/A * |
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External links
No external links available for Parg.
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| Pargtm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pargtm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |
| Pargtm2a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Pargtm2b(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Pargtm2e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |