Nubp2 | nucleotide binding protein 2

GeneMGI:1347072Synonyms: D17Wsu11e

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Limbs/digits/tail Skeleton Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating fructosamine level1 supporting datasetNubp2tm1b(EUCOMM)HmguheterozygoteEarly adult5.95x10-6 
preweaning lethality, complete penetrance1 supporting datasetNubp2tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
short tibia1 supporting datasetNubp2tm1b(EUCOMM)HmguheterozygoteEarly adult6.13x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nubp2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Nubp2tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Nubp2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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