Nubp2 | nucleotide binding protein 2
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Limbs/digits/tail Skeleton Mortality/aging
14 No significant impact
6 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating fructosamine level | 1 supporting dataset | Nubp2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 5.95x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Nubp2tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| short tibia | 1 supporting dataset | Nubp2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 6.13x10-5 |
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Human diseases caused by Nubp2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Nubp2.
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| Nubp2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Nubp2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Nubp2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |