Abcg2 | ATP binding cassette subfamily G member 2 (Junior blood group)

GeneMGI:1347061Synonyms: 4930430M16Rik, Bcrp

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye

15 No significant impact

7 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues

Phenotypes

fused cornea and lens1 supporting datasetAbcg2tm1.1(KOMP)VlcgheterozygoteEarly adult7.42x10-5 
decreased blood urea nitrogen level1 supporting datasetAbcg2tm1.1(KOMP)VlcghomozygoteEarly adult2.67x10-5 
increased circulating HDL cholesterol level1 supporting datasetAbcg2tm1.1(KOMP)VlcghomozygoteEarly adult1.62x10-6 
increased circulating cholesterol level1 supporting datasetAbcg2tm1.1(KOMP)VlcghomozygoteEarly adult3.46x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Abcg2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Abcg2tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Abcg2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Abcg2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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