Decr2 | 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Respiratory system Behavior/neurological Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating creatinine level1 supporting datasetDecr2tm1b(EUCOMM)WtsihomozygoteEarly adult3.89x10-10 
increased grip strength2 supporting datasetsDecr2tm1b(EUCOMM)WtsihomozygoteEarly adult5.23x10-6 
increased heart rate variability1 supporting datasetDecr2tm1b(EUCOMM)WtsihomozygoteEarly adult1.65x10-6 
increased pulmonary respiratory rate1 supporting datasetDecr2tm1b(EUCOMM)WtsihomozygoteEarly adult9.3x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Decr2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Decr2tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Decr2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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