Gnpda1 | glucosamine-6-phosphate deaminase 1
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Reproductive system Immune system Embryo Growth/size/body region Hematopoietic system Mortality/aging Renal/urinary system
13 No significant impact
4 Not tested
Data collections
Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Gnpda1tm1b(KOMP)Mbp | homozygote | E12.5 | N/A * | ||
| abnormal uterus morphology | 1 supporting dataset | Gnpda1tm1b(KOMP)Mbp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Gnpda1tm1b(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Gnpda1tm1b(KOMP)Mbp | homozygote | E9.5 | N/A * | ||
| small kidney | 1 supporting dataset | Gnpda1tm1b(KOMP)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Gnpda1tm1b(KOMP)Mbp | homozygote | E9.5 | N/A * | ||
| increased neutrophil cell number | 1 supporting dataset | Gnpda1tm1b(KOMP)Mbp | heterozygote | Early adult | 9.4x10-7 |
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External links
No external links available for Gnpda1.
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| Gnpda1tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Gnpda1tm1b(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | mouse |