Clcn6 | chloride channel, voltage-sensitive 6

GeneMGI:1347049

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	2 supporting datasets	Clcn6^em1(IMPC)Mbp	homozygote	Early adult	1.51x10^-10
abnormal eye morphology	1 supporting dataset	Clcn6^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased freezing behavior	1 supporting dataset	Clcn6^em1(IMPC)Mbp	homozygote	Early adult	1.06x10^-5
microphthalmia	1 supporting dataset	Clcn6^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Clcn6.

Associated images

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Histopathology

There is no histopathology data found for Clcn6.

IMPC related publications

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External links

No external links available for Clcn6.

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*Clcn6^em1(IMPC)Mbp*	Inter-exon deletion	‌	mouse
*Clcn6^{tm294269(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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