Map3k7 | mitogen-activated protein kinase kinase kinase 7
Physiological systems
21 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Mortality/aging
18 No significant impact
3 Not tested
Gene metrics:4Significant phenotypes
4Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues
| abnormal lens morphology | 1 supporting dataset | Map3k7tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 3.98x10-6 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Map3k7tm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Map3k7tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 2.71x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Map3k7tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Map3k7.
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| Map3k7tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Map3k7tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Map3k7tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Map3k7tm33755(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |