Map2k2 | mitogen-activated protein kinase kinase 2

GeneMGI:1346867Synonyms: Prkmk2, MAP kinase/Erk kinase, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Growth/size/body region Hematopoietic system Behavior/neurological

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

3Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal gait	1 supporting dataset	Map2k2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.9x10^-5
increased mean corpuscular volume	1 supporting dataset	Map2k2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.54x10^-5
decreased body weight	3 supporting datasets	Map2k2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.01x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Map2k2.

Associated images

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Histopathology

There is no histopathology data found for Map2k2.

IMPC related publications

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External links

No external links available for Map2k2.

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*Map2k2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Map2k2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Map2k2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes