Sh3yl1 | Sh3 domain YSC-like 1

GeneMGI:1346118Synonyms: YSC84, Ray

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity2 supporting datasetsSh3yl1em1(IMPC)MbphomozygoteEarly adult1.81x10-5 
abnormal eye morphology1 supporting datasetSh3yl1em1(IMPC)MbphomozygoteEarly adultN/A * 
increased monocyte cell number2 supporting datasetsSh3yl1em1(IMPC)MbphomozygoteEarly adult5.21x10-9 
microphthalmia1 supporting datasetSh3yl1em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sh3yl1em1(IMPC)MbpExon Deletionmouse
Sh3yl1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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