Jtb | jumping translocation breakpoint

GeneMGI:1346082

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Integument Vision/eye Cardiovascular system Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:50Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal skin coloration	1 supporting dataset	Jtb^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.7x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Jtb^{tm1b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Jtb^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal retina blood vessel morphology	1 supporting dataset	Jtb^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	6.64x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Jtb.

Associated images

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Histopathology

There is no histopathology data found for Jtb.

IMPC related publications

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External links

No external links available for Jtb.

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*Jtb^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Jtb^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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