Tlk2 | tousled-like kinase 2 (Arabidopsis)

GeneMGI:1346023Synonyms: PKUalpha, 4933403M19Rik, +1 more

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Embryo Skeleton Mortality/aging

13 No significant impact

8 Not tested

Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal bone structure1 supporting datasetTlk2em1(IMPC)BayheterozygoteEarly adult9.39x10-9 
abnormal embryo turning1 supporting datasetTlk2em1(IMPC)BayhomozygoteE9.5N/A * 
increased bone mineral content2 supporting datasetsTlk2em1(IMPC)BayheterozygoteEarly adult3.37x10-9 
preweaning lethality, complete penetrance3 supporting datasetsTlk2em1(IMPC)BayhomozygoteEarly adultN/A * 
prenatal lethality prior to heart atrial septation1 supporting datasetTlk2em1(IMPC)BayhomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tlk2em1(IMPC)BayExon Deletionmouse
Tlk2tm181271(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Tlk2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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