Mars1 | methionine-tRNA synthetase 1

GeneMGI:1345633Synonyms: methionine tRNA ligase, Mars, +2 more

Physiological systems

15 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

13 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

7Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	3 supporting datasets	Mars1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal locomotor behavior	1 supporting dataset	Mars1^em1(IMPC)Bay	heterozygote	Early adult	2.57x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mars1.

Associated images

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Histopathology

There is no histopathology data found for Mars1.

IMPC related publications

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External links

No external links available for Mars1.

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*Mars1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Mars1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mars1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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