Slc30a4 | solute carrier family 30 (zinc transporter), member 4
Physiological systems
19 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Renal/urinary system
9 No significant impact
5 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased grip strength | 1 supporting dataset | Slc30a4em1(IMPC)Tcp | homozygote | Early adult | 6.24x10-6 | ||
| short tibia | 1 supporting dataset | Slc30a4em1(IMPC)Tcp | homozygote | Early adult | 1.22x10-12 | ||
| increased grip strength | 1 supporting dataset | Slc30a4em1(IMPC)Tcp | homozygote | Late adult | 6.09x10-6 | ||
| tremors | 1 supporting dataset | Slc30a4em1(IMPC)Tcp | homozygote | Late adult | 7.59x10-6 | ||
| small thymus | 1 supporting dataset | Slc30a4em1(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Slc30a4em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal ovary morphology | 1 supporting dataset | Slc30a4em1(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| short tibia | 1 supporting dataset | Slc30a4em1(IMPC)Tcp | homozygote | Late adult | 6.21x10-7 | ||
| small adrenal glands | 1 supporting dataset | Slc30a4em1(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| enlarged kidney | 1 supporting dataset | Slc30a4em1(IMPC)Tcp | homozygote | Early adult | N/A * |
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Human diseases caused by Slc30a4 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Slc30a4.
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| Slc30a4em1(IMPC)Tcp | Exon Deletion | | mouse |
| Slc30a4tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Slc30a4tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Slc30a4tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Slc30a4tm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Slc30a4tm43906(L1L2_gt1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |