Slc30a4 | solute carrier family 30 (zinc transporter), member 4

GeneMGI:1345282Synonyms: Znt4

Physiological systems

19 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Renal/urinary system

9 No significant impact

5 Not tested

Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength1 supporting datasetSlc30a4em1(IMPC)TcphomozygoteEarly adult6.24x10-6 
short tibia1 supporting datasetSlc30a4em1(IMPC)TcphomozygoteEarly adult1.22x10-12 
increased grip strength1 supporting datasetSlc30a4em1(IMPC)TcphomozygoteLate adult6.09x10-6 
tremors1 supporting datasetSlc30a4em1(IMPC)TcphomozygoteLate adult7.59x10-6 
small thymus1 supporting datasetSlc30a4em1(IMPC)TcphomozygoteLate adultN/A * 
abnormal skin morphology1 supporting datasetSlc30a4em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal ovary morphology1 supporting datasetSlc30a4em1(IMPC)TcphomozygoteLate adultN/A * 
short tibia1 supporting datasetSlc30a4em1(IMPC)TcphomozygoteLate adult6.21x10-7 
small adrenal glands1 supporting datasetSlc30a4em1(IMPC)TcphomozygoteLate adultN/A * 
enlarged kidney1 supporting datasetSlc30a4em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc30a4em1(IMPC)TcpExon Deletionmouse
Slc30a4tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Slc30a4tm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Slc30a4tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Slc30a4tm2e(KOMP)WtsiTargeted, non-conditional allelees cell
Slc30a4tm43906(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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