Tenm1 | teneurin transmembrane protein 1

GeneMGI:1345185Synonyms: TCAP-1, teneurin-1, +2 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular hemoglobin concentration1 supporting datasetTenm1em1(IMPC)TcphomozygoteEarly adult1.78x10-15 
decreased mean corpuscular volume1 supporting datasetTenm1em1(IMPC)TcphemizygoteEarly adult2x10-10 
decreased exploration in new environment1 supporting datasetTenm1em1(IMPC)TcphemizygoteEarly adult1.66x10-7 
increased circulating alanine transaminase level1 supporting datasetTenm1em1(IMPC)TcphemizygoteEarly adult6.26x10-5 
decreased mean corpuscular hemoglobin1 supporting datasetTenm1em1(IMPC)TcphemizygoteEarly adult6.06x10-5 
decreased hematocrit1 supporting datasetTenm1em1(IMPC)TcphomozygoteEarly adult2.05x10-6 
decreased mean corpuscular volume1 supporting datasetTenm1em1(IMPC)TcphomozygoteEarly adult6.66x10-16 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tenm1em1(IMPC)TcpExon Deletionmouse
Tenm1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tenm1tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tenm1tm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Tenm1tm40461(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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