Clec5a | C-type lectin domain family 5, member a

GeneMGI:1345151Synonyms: myeloid DAP12-associating lectin-1, MDL-1, +2 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

cornea opacity1 supporting datasetClec5aem1(IMPC)MbphomozygoteEarly adult8.05x10-6 
decreased body length1 supporting datasetClec5aem1(IMPC)MbphomozygoteEarly adult7.38x10-13 
enlarged thymus1 supporting datasetClec5aem1(IMPC)MbphomozygoteEarly adultN/A * 
persistence of hyaloid vascular system1 supporting datasetClec5aem1(IMPC)MbphomozygoteEarly adult2.6x10-7 
eye hemorrhage1 supporting datasetClec5aem1(IMPC)MbphomozygoteEarly adult1.61x10-5 
abnormal thymus morphology1 supporting datasetClec5aem1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Clec5aem1(IMPC)MbpInter-exon deletionmouse
Clec5atm45167(L1L2_st1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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