Chic1 | cysteine-rich hydrophobic domain 1

GeneMGI:1344694Synonyms: Gm10454, Brx

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased red blood cell distribution width1 supporting datasetChic1em1(IMPC)TcphomozygoteEarly adult3.58x10-5 
decreased grip strength1 supporting datasetChic1em1(IMPC)TcphomozygoteEarly adult5.1x10-5 
abnormal retina vasculature morphology1 supporting datasetChic1em1(IMPC)TcphomozygoteEarly adult7.62x10-8 
abnormal retina blood vessel morphology1 supporting datasetChic1em1(IMPC)TcphomozygoteEarly adult6.44x10-8 
decreased mean corpuscular hemoglobin1 supporting datasetChic1em1(IMPC)TcphemizygoteEarly adult7.81x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Chic1em1(IMPC)TcpExon Deletionmouse
Chic1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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