Ubd | ubiquitin D

GeneMGI:1344410Synonyms: Diubiquitin, FAT10

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Hematopoietic system Behavior/neurological

16 No significant impact

3 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:78Adult tissues
36Embryo tissues

Phenotypes

abnormal seminal vesicle morphology1 supporting datasetUbdtm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
small thymus1 supporting datasetUbdtm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased CD4-positive, CD25-positive NK T cell number1 supporting datasetUbdtm1b(EUCOMM)WtsihomozygoteEarly adult1.73x10-6 
decreased memory-marker CD4-positive NK T cell number1 supporting datasetUbdtm1b(EUCOMM)WtsihomozygoteEarly adult2.1x10-9 
abnormal thymus morphology1 supporting datasetUbdtm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
impaired contextual conditioning behavior1 supporting datasetUbdtm1b(EUCOMM)WtsihomozygoteEarly adult8.24x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ubdtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Ubdtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ubdtm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ubdtm1c(EUCOMM)WtsiWild type floxed exon (post-Flp)mouse

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