Capn10 | calpain 10

GeneMGI:1344392Synonyms: Capn8

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Limbs/digits/tail Behavior/neurological Skeleton

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

short tibia2 supporting datasetsCapn10tm1b(EUCOMM)WtsihomozygoteEarly adult1.22x10-9 
increased circulating bilirubin level1 supporting datasetCapn10tm1b(EUCOMM)WtsihomozygoteEarly adult3.13x10-5 
abnormal cholesterol homeostasis1 supporting datasetCapn10tm1b(EUCOMM)WtsihomozygoteEarly adult7.2x10-7 
increased circulating phosphate level1 supporting datasetCapn10tm1b(EUCOMM)WtsihomozygoteEarly adult4.48x10-5 
hyperactivity1 supporting datasetCapn10tm1b(EUCOMM)WtsihomozygoteEarly adult3.02x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Capn10tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Capn10tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Capn10tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Capn10tm44789(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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