Chd4 | chromodomain helicase DNA binding protein 4

GeneMGI:1344380Synonyms: Mi-2beta, D6Ertd380e, +1 more

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:49Adult tissues

62Embryo tissues

Phenotypes

Life Stage:



embryonic lethality prior to organogenesis	1 supporting dataset	Chd4^{tm1b(EUCOMM)Wtsi}	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Chd4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Chd4.

Associated images

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Histopathology

There is no histopathology data found for Chd4.

IMPC related publications

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External links

No external links available for Chd4.

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*Chd4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Chd4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Chd4^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Chd4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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