Prkra | protein kinase, interferon inducible double stranded RNA dependent activator
Physiological systems
15 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Nervous system Hearing/vestibular/ear Behavior/neurological
10 No significant impact
9 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal ear morphology | 1 supporting dataset | Prkraem1(IMPC)H | homozygote | Early adult | 4.86x10-22 | ||
| decreased circulating alkaline phosphatase level | 1 supporting dataset | Prkraem1(IMPC)H | homozygote | Early adult | 1.54x10-5 | ||
| increased freezing behavior | 2 supporting datasets | Prkraem1(IMPC)H | homozygote | Early adult | 1.83x10-6 | ||
| increased circulating cholesterol level | 1 supporting dataset | Prkraem1(IMPC)H | homozygote | Early adult | 3.91x10-5 | ||
| male infertility | 1 supporting dataset | Prkraem1(IMPC)H | homozygote | Early adult | N/A * | ||
| increased grip strength | 2 supporting datasets | Prkraem1(IMPC)H | homozygote | Early adult | 6.11x10-14 | ||
| increased blood urea nitrogen level | 1 supporting dataset | Prkraem1(IMPC)H | homozygote | Early adult | 6.78x10-6 | ||
| decreased prepulse inhibition | 3 supporting datasets | Prkraem1(IMPC)H | homozygote | Early adult | 2.63x10-5 |
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External links
No external links available for Prkra.
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| Prkraem1(IMPC)H | Exon Deletion | | mouse |
| Prkraem2(IMPC)H | Exon Deletion | | mouse |
| Prkratm372742(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |