Cdh18 | cadherin 18

GeneMGI:1344366Synonyms: B230220E17Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased exploration in new environment1 supporting datasetCdh18em1(IMPC)JhomozygoteEarly adult1.6x10-5 
decreased circulating calcium level1 supporting datasetCdh18em1(IMPC)JhomozygoteEarly adult1.64x10-6 
increased exploration in new environment1 supporting datasetCdh18em1(IMPC)JhomozygoteEarly adult2.42x10-6 
hyperactivity1 supporting datasetCdh18em1(IMPC)JhomozygoteEarly adult1.27x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cdh18em1(IMPC)JExon Deletionmouse
Cdh18em1(IMPC)WtsiExon Deletionmouse
Cdh18tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Cdh18tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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