Arih2 | ariadne RBR E3 ubiquitin protein ligase 2

GeneMGI:1344361Synonyms: TRIAD1

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Integument Embryo Growth/size/body region Mortality/aging Renal/urinary system

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

30Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic growth retardation	1 supporting dataset	Arih2^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Arih2^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Arih2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
cystolithiasis	1 supporting dataset	Arih2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Arih2^{tm1.1(KOMP)Vlcg}	heterozygote	E9.5	N/A ^*
abnormal kidney morphology	1 supporting dataset	Arih2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Arih2^{tm1.1(KOMP)Vlcg}	heterozygote	E9.5	N/A ^*
abnormal urinary bladder morphology	1 supporting dataset	Arih2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Arih2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
polycystic kidney	1 supporting dataset	Arih2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arih2.

Associated images

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Histopathology

There is no histopathology data found for Arih2.

IMPC related publications

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External links

No external links available for Arih2.

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*Arih2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Arih2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Arih2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Arih2^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Arih2^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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