Car14 | carbonic anhydrase 14

GeneMGI:1344341Synonyms: CA XIV

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological Cardiovascular system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased total retina thickness	2 supporting datasets	Car14^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.43x10^-19
abnormal retina morphology	1 supporting dataset	Car14^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.74x10^-10
abnormal retina vasculature morphology	1 supporting dataset	Car14^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.86x10^-8
decreased respiratory quotient	1 supporting dataset	Car14^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.56x10^-6
decreased food intake	1 supporting dataset	Car14^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.69x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Car14^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.73x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Car14.

Associated images

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Histopathology

There is no histopathology data found for Car14.

IMPC related publications

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External links

No external links available for Car14.

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*Car14^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Car14^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Car14^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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