Klk8 | kallikrein related-peptidase 8

GeneMGI:1343327Synonyms: BSP1, Prss19, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Growth/size/body region Hematopoietic system Renal/urinary system

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lymphocyte cell number	1 supporting dataset	Klk8^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.26x10^-5
enlarged spleen	1 supporting dataset	Klk8^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Klk8^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Klk8^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Klk8.

Associated images

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Histopathology

There is no histopathology data found for Klk8.

IMPC related publications

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External links

No external links available for Klk8.

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*Klk8^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Klk8^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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