Vgf | VGF nerve growth factor inducible

GeneMGI:1343180Synonyms: LOC381677

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Limbs/digits/tail Nervous system Behavior/neurological Skeleton Cardiovascular system

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating glucose level1 supporting datasetVgfem1(IMPC)HhomozygoteEarly adult2.16x10-8 
increased grip strength1 supporting datasetVgfem1(IMPC)HhomozygoteEarly adult1.24x10-5 
hyperactivity6 supporting datasetsVgfem1(IMPC)HhomozygoteEarly adult1.59x10-28 
decreased circulating fructosamine level1 supporting datasetVgfem1(IMPC)HhomozygoteEarly adult1.5x10-8 
abnormal locomotor behavior1 supporting datasetVgfem1(IMPC)HhomozygoteEarly adult1.22x10-10 
increased circulating total protein level1 supporting datasetVgfem1(IMPC)HhomozygoteEarly adult9.52x10-5 
increased exploration in new environment1 supporting datasetVgfem1(IMPC)HhomozygoteEarly adult1.2x10-6 
increased circulating alanine transaminase level1 supporting datasetVgfem1(IMPC)HhomozygoteEarly adult2.21x10-12 
decreased prepulse inhibition1 supporting datasetVgfem1(IMPC)HhomozygoteEarly adult2.6x10-7 
limb grasping1 supporting datasetVgfem1(IMPC)HhomozygoteEarly adult4.8x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Vgfem1(IMPC)HIndelmouse
Vgfem1(IMPC)WtsiPoint Mutationmouse

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