Dctn6 | dynactin 6

GeneMGI:1343154Synonyms: WS-3, p27

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Nervous system Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to organogenesis	1 supporting dataset	Dctn6^em1(IMPC)J	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Dctn6^em1(IMPC)J	homozygote	Early adult	N/A ^*
decreased prepulse inhibition	1 supporting dataset	Dctn6^em1(IMPC)J	heterozygote	Early adult	5.61x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dctn6.

Associated images

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Histopathology

There is no histopathology data found for Dctn6.

IMPC related publications

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External links

No external links available for Dctn6.

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*Dctn6^em1(IMPC)J*	Exon Deletion	‌	mouse
*Dctn6^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dctn6^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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