Kat2b | K(lysine) acetyltransferase 2B

GeneMGI:1343094Synonyms: Pcaf, A930006P13Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased mean corpuscular hemoglobin	1 supporting dataset	Kat2b^{em1(IMPC)Wtsi}	homozygote	Early adult	4.31x10^-10
impaired glucose tolerance	1 supporting dataset	Kat2b^{em1(IMPC)Wtsi}	homozygote	Early adult	9.33x10^-6
increased red blood cell distribution width	1 supporting dataset	Kat2b^{em1(IMPC)Wtsi}	homozygote	Early adult	5.4x10^-7
decreased circulating cholesterol level	1 supporting dataset	Kat2b^{em1(IMPC)Wtsi}	homozygote	Early adult	2.73x10^-5
decreased circulating HDL cholesterol level	1 supporting dataset	Kat2b^{em1(IMPC)Wtsi}	homozygote	Early adult	1.73x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kat2b.

Associated images

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Histopathology

There is no histopathology data found for Kat2b.

IMPC related publications

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External links

No external links available for Kat2b.

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*Kat2b^{em1(IMPC)Wtsi}*	Deletion	‌	mouse
*Kat2b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Kat2b^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Kat2b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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