Rbmx | RNA binding motif protein, X chromosome

GeneMGI:1343044

Physiological systems

22 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological Renal/urinary system

18 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

3Associated diseases

Expression examined in:156Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



increased kidney weight	2 supporting datasets	Rbmx^{tm2b(KOMP)Wtsi}	hemizygote	Early adult	6.04x10^-6
increased circulating insulin level	1 supporting dataset	Rbmx^{tm2a(KOMP)Wtsi}	homozygote	Early adult	1.93x10^-8
increased circulating chloride level	1 supporting dataset	Rbmx^{tm2b(KOMP)Wtsi}	hemizygote	Early adult	4.44x10^-16
decreased circulating calcium level	1 supporting dataset	Rbmx^{tm2b(KOMP)Wtsi}	hemizygote	Early adult	1.48x10^-10
increased grip strength	3 supporting datasets	Rbmx^{tm2b(KOMP)Wtsi}	homozygote	Early adult	4.33x10^-7
increased circulating alkaline phosphatase level	1 supporting dataset	Rbmx^{tm2b(KOMP)Wtsi}	homozygote	Early adult	5.49x10^-6
increased grip strength	1 supporting dataset	Rbmx^{tm2b(KOMP)Wtsi}	hemizygote	Early adult	7.39x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rbmx.

Associated images

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Histopathology

There is no histopathology data found for Rbmx.

IMPC related publications

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External links

No external links available for Rbmx.

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*Rbmx^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Rbmx^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Rbmx^{tm2b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rbmx^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Rbmx^{tm3a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Rbmx^{tm3e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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