Ikzf3 | IKAROS family zinc finger 3

GeneMGI:1342542Synonyms: Aiolos, 5830411O07Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Immune system Hematopoietic system

15 No significant impact

7 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:152Adult tissues
25Embryo tissues

Phenotypes

decreased leukocyte cell number1 supporting datasetIkzf3tm1(KOMP)VlcghomozygoteEarly adult5.75x10-14 
thrombocytopenia1 supporting datasetIkzf3tm1(KOMP)VlcghomozygoteEarly adult1.21x10-5 
increased neutrophil cell number1 supporting datasetIkzf3tm1(KOMP)VlcghomozygoteEarly adult3.76x10-7 
decreased lymphocyte cell number2 supporting datasetsIkzf3tm1(KOMP)VlcghomozygoteEarly adult1.2x10-14 
decreased large unstained cell number1 supporting datasetIkzf3tm1(KOMP)VlcghomozygoteEarly adult3.32x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ikzf3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Ikzf3tm221089(L1L2_Bact_P)Reporter-tagged deletion allele (with selection cassette)targeting vector

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